AMES Courses

AMES 10. FORTRAN for Engineers (4). FORTRAN computer programming language and its application to the solution of numerical problems. Command and editing in the interactive mode. Emphasis on good programming practices.

AMES 15. Introduction to Engineering Graphics and Design (4). Introduction to engineering graphics and computer-aided design (CAD). Engineering graphics topics include orthographic, oblique, and axonometric projections; auxiliary and sectional views; and dimensioning. AutoCAD and C programming assignments for 3-D graphics and solid modeling. Guest lectures on engineering design. Prerequisites: Grade of C- or better in AMES 10.

AMES 103A. Introduction to Fluid Mechanics (4). Equations of motion; non-Newtonian fluids; hydrostatics; Bernoulliís equation; viscous flows; turbulent, applications to chemical engineering, bioengineering, and structural engineering. (Students may not receive credit for both AMES 101A and AMES 103A). Prerequisites: Admission to the major and grades of C- or better in Phys. 2A and Math 21D or 20D, 20E.

AMES 103B. Mass Transfer (4). Diffusive and convective mass transfer in solids, liquids, and gases; steady and unsteady state; mass transfer coefficients; applications to chemical engineering and bioengineering. Prerequisites: Admission to the major and AMES 103A or 101A with a grade of C- or better.

AMES 105. Introduction to Mathematical Physics (4). Fourier series. Sturm-Liouville theory, elementary partial differential equations, integral transforms with applications to problems in vibration, wave motion, and heat conduction. Prerequisites: Admission to the major and grades of C- or better in Phys. 2A-2B and Math 21D or 20D.

AMES 121A. Mechanics I: Static (4). Principles of statics. Three-dimensional equilibrium analysis with unit vector representation. Analysis of simple, statically determinate structures under discrete and distributed loading; hydrostatics, internal forces of beams. Problem formulation and problem solution with application to realistic engineering problems. Prerequisites: Math 21C or math 20D and Phys. 2A with grades of C- or better.

AMES 121B. Mechanics II: Dynamics (4). Kinematics and kinetics of particles in three-dimensional vector representation; orbital mechanics. Work, energy and power for particle motion, conservative forces and conservation principles. Principle of impulse and momentum, impulsive motion and impact. Relative motion and conservation principles for systems of particles with variable mass; applications to fluid flow and rocket propulsion. Rigid body kinematics, rolling and sliding motions. Impact of rigid bodies. One-degree of freedom undamped vibrating systems resonance under sinusoidal excitation. Lectures include methods of problems formulation and problem solution with application to realistic engineering problems. Prerequisites: Math 20D or 21D and AMES 121A with grades of C- or better.

AMES 130A. Solid Mechanics I (4). Mechanics of deformable bodies under axial, torsional, shearing, and bending loads. Elastic and plastic uniaxial material response as well as three-dimensional Hookeís Law. Mohrís circle for stress and strain. Problems of design for rods, shafts, beams, columns, pressure vessels and thin-walled members. Problems of design for pressure vessels, circular shafts, thin-walled members, and standard rolled-steel shapes. Prerequisites: Grades of C- or better in Math 20D or 21D, 20F; and AMES 121A.

AMES 153. Process Modeling and Computation in Chemical Engineering (4). Introduction to elementary numerical methods with applications to chemical engineering problems using a variety of problem solving strategies, Error analysis, Concepts of mathematical modeling, material and energy balances and probability and statistics with applications to design problems. Prerequisites: Admission to the major and grades of C- or better in AMES 9 or AMES 10.

AMES 154. Numerical methods in Engineering (4). This course discusses numerical methods for applications for engineering problems. Topics include solution of systems of linear and nonlinear equations, function interpolation and curve fitting function approximation, computation of integral, numerical differentiation, and solution of systems of ordinary differential equations. Prerequisites: Admission to the major and grades of C- or better in AMES 10 and Math 20F.

AMES 156AóB. Mechanical Engineering Design I, II (4). Fundamental principles of mechanical design. application of engineering mechanics to the design of mechanical components. Design project involving a preliminary design for a realistic engineering application. Prerequisites: Admission to the major and grades of C- or better in AMES 11 or AMES 102, 15, 121AóB, and 130A. Enrollment in AMES 156B requires grades of C- or better in AMES 156A and 158 (or concurrent enrollment).

AMES 158. Computer-Aided Analysis and Design (4). The use of computers for the design and analyses of engineering systems. Prerequisites: Admission to the major and grades of C- or better in AMES 130 B, 154, and concurrent enrollment in AMES 101A or AMES 1031.

AMES 163. Linear circuits (4). Steady-state and dynamic behavior of linear, lumped-parameter systems, including electrical, mechanical, and thermal. Kirchoffís laws. RLC circuits. Amplifiers. Dependent sources. Response of first- and second-order systems to impulse and step inputs. Laplace-transforms. Design applications in engineering. Prerequisites: Admission to the major and grades of C- or better in Math 21D or Math 20D, math 20F and Phys. 2B.

AMES 170. Experimental Techniques (4). Principles and practice of measurement and control and the design and conduct of experiments. Technical report writing. Lectures relate to dimensional analysis, error analysis, signal-to-noise problems, filtering, data acquisition and data reduction, as well as background of experiments and statistical analysis. Experiments relate to the use of electronic devices and sensors. Prerequisites: Grade of C- or better in AMES 163 and junior standing in major, and Phys. 2CL.

Bioengineering Courses

BE 1. Introduction to Bioengineering (1). An introduction to Bioengineering in a seminar format. The principles of problem definition, team design, engineering inventiveness, information access, communication, ethics, and social responsibility will be emphasized. P/NP grading only. Prerequisites: none.

BE 90. Undergraduate Seminar (1). Selected topics of interest to the faculty will be used to introduce students to bioengineering science and design concepts. (Not open to upper-division bioengineering students.)

BE 100. Introduction to Bioengineering Design (4). A general introduction to Bioengineering design, including examples of engineering analysis and design applied to representative topics in biomechanics, bioinstrumentation, biomaterials, biotechnology, and related areas. A review of technological needs, design methodology, testing procedures, statistical analysis, governmental regulation, evaluation of costs and benefits, quality of life, and ethical issues. Prerequisites: Grade of C- or better in Math 21C and Phys. 2C.

BE 110. Continuum Mechanics (4). An introduction to continuum mechanics of both living and non-living bodies. The laws of motion and free-body diagrams. Stresses. Deformation. Compatibility conditions. Constitutive equations. Properties of common fluids and solids. Derivation of field equations and boundary conditions. Applications to bioengineering design. Prerequisites: Admission to the major and grades of C- or better in Phys. 2AóC.

BE 112A. Biomechanics (4). Introduction to physiological systems, with emphasis on structure and function of major tissues and organs. Application of mechanics to understand the behavior of these tissues and organs at gross and microscopic levels. Design of surgical procedures and prosthetic devices. Prerequisites: Admission to the major and grade of C- or better in BE 110.

BE 112B. Biomechanics (4). Bioviscoelastic fluids and solids. Non-newtonian behavior of blood, synovial fluid, mucus, and protoplasm. Basic mechanical properties of collagen and elastin, bone, cartilage, muscles, blood vessels, and other living tissues. Application of continuum mechanics at great depth. Artificial implantable materials and design of prosthetic devices. Prerequisites: Admission to the major and grade of C- or better in BE 112A.

BE 122A. Biosystems and Control (4). Systems and control theory applied to bioengineering. Modeling, linearization, transfer functions, Laplace transforms, closed-loop systems, design and simulation of controllers. Dynamic behavior and control of first and second order processes. PID controllers. Stability. Bode design. Features of biological control systems. A simulation term project using MATLAB and an oral presentation are required. Prerequisites: Admission to the major and grade of C- or better in AMES 163.

BE 122B. Biomedical Electronics (4). Measurement circuits and signal analysis in biological systems and medicine. Passive and active circuits. Semiconductors. Operational amplifiers. Nonlinear devices. Signals in continuous and discrete time systems. Modulation. Digital signal processing. Sampling. Noise. Digital filters. Computer design and use for biomedical instrumentation. A term project and oral presentation are required. Prerequisites: Admission to the major and grade of C- or better in BE 122A.

BE 140A. Introduction to Bioengineering Physiology (4). Introductory mammalian physiology for bioengineering students, with an emphasis on control mechanisms and engineering principles. Nervous and cardiovascular systems. Not intended for premedical bioengineering students. Prerequisites: Admission to the major and grade of C- or better in BE 110.

BE 140B. Introduction to Bioengineering Physiology (4). Introductory mammalian physiology for bioengineering students, with an emphasis on control mechanisms and engineering principles. Renal and endocrine systems, considering regulation from molecular-cellular to organ systems level. Prerequisites: Admission to the major and grade of C- or better in BE 140A.

BE 160A. Metabolic Engineering (4). Engineering systems analysis of metabolic processes common to all living organisms. Kinetics of individual enzymatic reactions. Computer simulations of metabolic networks. The stoichiometric matrix, systemic sensitivity coefficients, bifurcations and redirection of metabolic fluxes. Temporal decompositions of metabolic processes into multiple time scales and the physiologic roles of metabolic events in each scale. Prerequisites: Grade of Có or better in BIBC 102 (may be concurrent), BE 122A and admission to the major.

BE 160B. Biochemical Engineering (4). Industrial microbial production strains, bioreactor and fermenter designs, bioprocess monitoring and control. Prerequisites: Grade of Có or better in BE 160A and admission to the major.

BE 160C. Biochemical Engineering (4). Bioseparations. Commercial production of biochemical commodity products. Prerequisites: Grade of Có or better in BE 160B and admission to the major.

BE 162. Biotechnology Laboratory (4). Laboratory practices and design principles for biotechnology. Culture of microorganisms and mammalian cells, recombinant DNA bioreactor design and operation. Design and implementation of biosensors. A team design-based term project and oral presentation required. Prerequisites: Grade of Có or better in AMES 170, co-registration in BE 160B.

BE 166A. Cell and Tissue Engineering (4). Engineering analysis of physico-chemical rate processes that affect, limit, and govern the function of cells and tissues. Cell migration, mitosis, apoptosis, and differentiation. Dynamic and structural interactions between mesenchyme and parenchyme. The role of the tissue microenvironment, extracellular matrix, and growth factor communication. The design of functional tissue units. Clinical Applications. Prerequisites: Co-registration in BE 160B and admission to the major.

BE 172. Bioengineering Laboratory (4). A laboratory course which demonstrates basic concepts of bioengineering design through experimental procedures involving humans and experimental animals. Statistical principles of experimental design. Study of possible errors. Experiments include nerve action, electrocardiography, mechanics of muscle, membranes, and noninvasive diagnostics in humans. Prerequisites: Admission to the major and grade of C- or better in AMES 170, and senior standing in the major.

BE 186A. Principles of biomaterials Design (4). Fundamentals of materials science as applied to bioengineering design. Natural and synthetic polymeric materials. Materials characterization and design. Wound repair, blood clotting, foreign body response, transplantation biology, biocompatibility of materials, tissue engineering. Artificial organs and medical devices. Government regulations. patenting. Ethical issues. A term project and oral presentation are required. Prerequisites: Admission to the major and grade of C- or better in BE 112B.

BE 186B. Principles of Bioinstrumentation Design (4). Biophysical phenomena, transducers, and electronics as related to the design of biomedical instrumentation. Potentiometric and amperometric signals and amplifiers. Biopotentials, membrane potentials, chemical sensors. Mechanical transducers for displacement, force, and pressure. Temperature sensors. Flow sensors. Light-based instrumentation. Electrical safety. A term project and oral presentation are required. Prerequisites: Admission to the major and grade of C- or better in AMES 163 and 170.

BE 186C. Bioengineering Design (4). Preparation of formal engineering reports on a series of engineering analysis and design problems illustrating methodology from various branches of applied mechanics as applied to bioengineering problems. Statistical analysis. Governmental regulations. Bioethical issues. A term project and oral presentation are required. Prerequisites: Admission to the major and grades of C- or better in AMES 103AóB, 121AóB, 154; BE 112B, 122B, and 186B.

BE 191A. Senior Seminar I: Professional Issues in Bioengineering (2). Role of bioengineers in industry. Professional identity. Structure of bioengineering industries and product development process. Job market analysis. Current employment opportunities. Recruiting process and interview. Analysis of the employer. Marketing vs engineering. Management by objective. Role of higher degrees. Prerequisite: Consent of instructor.

BE 195. Teaching (2ó4). Teaching and tutorial assistance in a bioengineering course under supervision of instructor. Not more than four units may be used to satisfy graduation requirements. (P/NP grades only.) Prerequisites: B average in the major and departmental approval.

BE 197. Engineering Internship (1ó4).An enrichment program, available to a limited number of undergraduate students, which provides work experience with industry, government offices, hospitals and their practices. Subject to the availability of positions, students will work in a local industry or hospital (on a salaried or unsalaried basis) under the supervision of a faculty member and industrial supervisor. Coordination of the Engineering Internship is conducted through UCSDís Academic Internship Program. Time and effort to be arranged. Units may not be applied toward major graduation requirements unless prior approval of a faculty adviser is obtained and internship is an unsalaried position. Prerequisites: Completion of ninety units with a 2.5 GPA and consent of a Bioengineering faculty coordinator.

BE 198. Directed Group Study (1ó4). Directed group study, on a topic or in a field not included in the regular department curriculum, by arrangement with a bioengineering faculty member. (P/NP grades only.) Prerequisite: Consent of instructor.

BE 199. Independent Study for Undergraduates (4). Independent reading or research by arrangement with a bioengineering faculty member. (P/NP grades only.) Prerequisite: Consent of instructor.

Biology/Animal Physiology and Neuroscience

BIPN 100. Mammalian Physiology I (4). This course introduces the concepts of physiological regulation, controlled and integrated by the nervous and endocrine systems. It then examines the muscular, cardiovascular, and renal systems in detail and considers their control through the interaction of nervous activity and hormones. Three hours of lecture and one hour of discussion. Prerequisites: BILD 1,2 and BIBC 100 or 102.

BIPN 102. Mammalian Physiology II (4). This course completes the survey of organ systems begun in BIPN 100, by considering the respiratory and gastrointestinal systems. Consideration is then given to interactions of these systems in weight and temperature regulation, exercise physiology, stress, and pregnancy and reproduction. Three hours of lecture and one hour of section per week. Prerequisite: BIPN 100.

BIPN 140. Cellular Neurobiology (4). This course covers the biophysics of the resting and active membranes of nerve cells. It also covers the mechanisms of sensory transduction and neuromodulation, as well as the molecular basis of nerve cell function. Prerequisites: BILD 1,2, and BIBC 100 or 102.

Molecular Biology, Microbiology

BIMM 100. Molecular Biology (4). Molecular analysis of gene action: DNA structure, replication, transcription, protein synthesis. Regulation of gene activity. Recombination, mutation, and introduction to genetic engineering. Emphasis on procaryotes, but with discussion of eucaryotes. Three hours of lecture and one hour of recitation. Prerequisites: BIBC 100 or 102 and BICD 100.

Biology/Genetics, Cellular, and Developmental Biology of Plants and Animals

BICD 100. Genetics (4). An Introduction to the principles of heredity in diploid organisms, fungi, bacteria, and viruses. Mendelian inheritance, population genetics; quantitative genetics; linkage; sex determination; meiotic behavior of chromosome aberrations, gene structure, regulation, and replication; genetic code. Three hours of lecture and one hour of recitation. Prerequisite: BILD 1 or the equivalent.

Biology/Biochemistry

BIBC 100. Structural Biochemistry (4). The structure and function of biomolecules. Includes proteins conformation, dynamics, and function; enzymatic catalysis and allosteric regulation, lipids and membranes, sugars and polysaccarides, and nucleic acids. Three hours of lecture and one hour of recitation. Prerequisites: two quarters of organic chemistry.

BIBC 102. Metabolic Biochemistry (4). Energy-producing pathways-glycolysis, the TCA cycle, oxidative phosphorylation, photosynthesis and fatty acid oxidation; and biosynthetic pathways-gluconeogenesis, glycogen synthesis and fatty acid biosynthesis. Three hours lecture and one hour recitation. Prerequisites: two quarters of organic chemistry (second quarter may be taken concurrently.

BIBC 103. Biochemical Techniques (6). A laboratory-lecture course in the applicacation of biochemical methods to bilogical problems. Three hours of lecture and eight hours of laboratory each week. In addition to the formal lab hours, there will be at least eight hours in which students will be required to work in the class laboratory to complete experiments and prepare for presentations. Prerequisite: BIBC 100 or 102.

Chemistry Courses

CHEM 6A. General Chemistry (4). First quarter of a three-quarter sequence intended for science and engineering majors. Topics include: stoichiometry, gas laws, bonding, atomic theory, quantum theory, and thermochemistry. Three hoursí lecture, one hour recitation. Prerequisites: proficiency in high school chemistry or physics and in high school mathematics; Math 4C or equivalent.

CHEM 6B. General Chemistry (4). Second quarter of a three-quarter sequence intended for science and engineering majors. Topics include: molecular geometry, condensed phases and solutions, chemical equilibrium, acids and bases and thermodynamics. Three hoursí lecture, one hour recitation. Prerequisites: Chem. 6A; Math 20A or 1A.

CHEM 6BL. Introductory Inorganic Chemistry Laboratory (2). Introduction to experimental procedures used in synthetic, analytical, and physical chemistry. If 6BL is a requirement for your major, it should be taken concurrently with 6B, or 6C.

CHEM 6C. General Chemistry (4). Third quarter of a three-quarter sequence intended for science and engineering majors. Topics include: electrochemistry, kinetics, coordination chemistry, nuclear chemistry, and an introduction to organic and biochemistry. Three hoursí lecture, one hour recitation. Prerequisites: Chem. 6B; Chem. 6BL may be taken concurrently.

CHEM 131. Physical Chemistry (4). Thermodynamics, chemical equilibrium, phase equilibrium, chemistry of solutions. Prerequisites: Chem. 6C, Math 20C, 20D, or consent of instructor. (Note: Students may not receive credit for both 131 and 127.)

CHEM 140A. Organic Chemistry (4). Chem. 141A introduces theoretical and experimental studies of structure and properties of covalent molecules. Both resonance and simple molecular orbital descriptions of organic compounds are introduced and spectroscopic methods for determining electronic and molecular structure are discussed. Organic reactions are introduced with synthetic and mechanistic examples. Prerequisites: Chem. 6C (6C may be taken concurrently by good students). Prior or concurrent physics recommended. (Note: Students may not receive credit for both Chem. 141A and Chem. 140A.)

CHEM. 140B. Organic Chemistry (4). A continuation of 141A, this course applies the structure-reactivity, spectroscopy, and electronic theories introduced in 141A to organic reactions. Prerequisite: Chem. 141A. (Note: Students may not receive credit for both Chem. 141B and Chem. 140B.)

CHEM. 143A. Organic Chemistry Laboratory (3). Introduction to laboratory techniques needed in organic chemistry. Stresses physical methods including separation and purification, spectroscopy, product analysis and effects of reaction conditions. Prerequisites: Chem. 6BL, Chem. 141A or Chem. 140A. (Note: Students may not receive credit for both Chem. 143A and Chem. 143AM.)

Mathematics Courses

MATH 20A. Calculus (4). Foundations of differential and integral calculus of one variable. Functions, graphs, continuity, limits, derivative, tangent line. Applications with algebraic, exponential, logarithmic, and trigonometric functions. Introduction to the integral. Prerequisite: Passing score on placement examination or completion of Math 4C with a grade of B or better.

MATH 20B. Calculus (4). Integral calculus of one variable and its applications, with exponential logarithmic, hyperbolic, and trigonometric functions. Methods of integration. Polar coordinates in the plane. Prerequisite: Math 20A or equivalent/Score of 4 or better on AB calculus AP test.

MATH 21C. Calculus and Analytic Geometry (4). Vector geometry, vector functions and their derivatives. Partial differentiation. Maxima and minima. Double integration. Prerequisite: Math 20B or equivalent or consent of instructor.

MATH 21D. Introduction to Differential Equations (4). Infinite series. Ordinary differential equations: exact, separable, and linear; constant coefficients, undetermined coefficients, variation of parameters. Series solutions. Systems, Laplace transforms. Technique for engineering. Prerequisite: Math 21C or equivalent or consent of instructor.

MATH 20E. Vector Calculus (4). Change of variable in multiple integrals, Jacobian. Line integrals, Greenís theorem. Vector fields, gradient fields, divergence, curl. Spherical and cylindrical coordinates. Taylor series in several variables. Surface integrals, Stokeís theorem. Gauss theorem and its applications. Conservative fields. Prerequisite: Math 20D (or 21D) or consent of instructor.

MATH 20F. Linear Algebra (4). Matrix algebra, solution of systems of linear equations by Gaussian elimination, determinants. Linear and affine subspaces, bases of Euclidean spaces. Eigenvalues and eigenvectors, quadratic forms, orthogonal matrices, diagonalization of symmetric matrices. Applications. Prerequisite: Math 20B. Math 20D strongly recommended.

Physics Courses

PHYS 2A. Physics-Mechanics (4). A calculus-based science-engineering general physics course covering vectors, motion in one and two dimensions, Newtonís first and second laws, work and energy, conservation of energy, linear momentum, collisions, rotational kinematics, rotational dynamics, equilibrium of rigid bodies, oscillations, gravitation. Prerequisites: Math. 20A, and concurrent enrollment in Math. 20B.

PHYS 2B. Physics-Electricity and Magnetism (4). Continuation of Physics 2A covering charge and matter, the electric field, Gaussís law, electric potential, capacitors and dielectrics, current and resistance, electromotive force and circuits, the magnetic field, Ampereís law, Faradayís law, inductance, electromagnetic oscillations, alternating currents and Maxwellís equations. Prerequisites: Phys. 2A, Math. 20B, and concurrent enrollment in Math. 20C or 21C.

PHYS 2BL. Physics Laboratory-Mechanics and Electrostatics (2). One hour lecture and three hoursí laboratory. Experiments include gravitational force, linear and rotational motion, conservation of energy and momentum, collisions, oscillations and springs, gyroscopes. Experiments on electrostatics involve charge, electric field, potential, and capacitance. Data reduction and error analysis are required for written laboratory reports. Prerequisite: concurrent enrollment in Phys. 2B, 2BS, or 4C.

PHYS 2C. Physics-Fluids, Waves, Thermodynamics, and Optics (4). Continuation of Physics 2B covering fluid mechanics, waves in elastic media, sound waves, temperature, heat and the first law of thermodynamics, kinetic theory of gases, entropy and the second law of thermodynamics, Maxwellís equations, electromagnetic waves, geometric optics, interference and diffraction. Prerequisites: Phys. 2B, Math. 20C or 21C, and concurrent enrollment in Math 20D or 21D.

PHYS 2CL. Physics Laboratory-Electricity and magnetism, Waves, and Optics (2). One hour lecture and three hoursí laboratory. Experiments on refraction, interference/diffraction using lasers and microwaves; lenses and the ye; acoustics; oscilloscope and L-R-C circuits; oscillations, resonance and damping, mesurement of magnetic fields; and the mechanical equivalence of heat. (Students may not receive credit for both Physics 1CL and 2CL.) Prerequisites: Prior or concurrent enrollment in Physics 1C, 2C, 2CS, or 4D.